Achieving the UNAIDS 90–90-90 targets: a comparative analysis of four large community randomised trials delivering universal testing and treatment to reduce HIV transmission in sub-Saharan Africa - Sabapathy, K.; Balzer, L.; Larmarange, Joseph; Block, L.; Floyd, S.; Iwuji, C.; Wirth, K.; Ayles, H.; Fidler, S.; Kamya, M.; Petersen, M.; Havlir, D.; et al. (BMC Public Health, 2022)
Four large community-randomized trials examining universal testing and treatment (UTT) to reduce HIV transmission were conducted between 2012–2018 in Botswana, Kenya, Uganda, Zambia and South Africa. In 2014, the UNAIDS 90–90-90 targets were adopted as a useful metric to monitor coverage. We systematically review the approaches used by the trials to measure intervention delivery, and estimate coverage against the 90–90-90 targets. We aim to provide in-depth understanding of the background contexts and complexities that affect estimation of population-level coverage related to the 90–90-90 targets.
Keywords: journalArticle; Antiretroviral treatment; HIV; Treatment as Prevention; UNAIDS 90-90-90; Universal Testing and Treatment