Joseph Larmarange

Pilot Implementation of HIV Self-Testing Delivery in Private Pharmacies Combined With a Respondent-Driven Sampling Method to Improve HIV Testing for Men Who Have Sex With Men and Transgender Women in Phnom Penh (ANRS 0100s): Protocol for a Prospective Mixed Method Feasibility Study

Joseph LARMARANGE — 2025-06-27T09:45:00Z

Pilot Implementation of HIV Self-Testing Delivery in Private Pharmacies Combined With a Respondent-Driven Sampling Method to Improve HIV Testing for Men Who Have Sex With Men and Transgender Women in Phnom Penh (ANRS 0100s): Protocol for a Prospective Mixed Method Feasibility Study

Chhavarath Dary , Olivier Ségéral , Joseph Larmarange , Emilie Mosnier , Mohamed Ben Mechlia , Vichea Ouk , Bruno Spire , Vonthanak Saphonn

JMIR Research Protocols, 2025, 14, pp.e65351. ⟨10.2196/65351⟩

Article dans une revue

inserm-05471400

Authors

Chhavarath Dary, Olivier Ségéral, Joseph Larmarange, Emilie Mosnier, Mohamed Ben Mechlia, Vichea Ouk, Bruno Spire, Vonthanak Saphonn

Abstract

Background: Regular testing is recognized as a key strategy for HIV control. The 2023 Integrated Biological and Behavioral Survey (IBBS) in Cambodia revealed that nearly one-third of men who have sex with men (MSM) and one-fourth of transgender women (TGW) were never tested for HIV or not for more than 12 months. The majority of MSM and TGW were tested at community-based organizations (CBOs) facilities and by CBO outreach workers, while private facilities are poorly used for HIV testing (6% for MSM and 9% for TGW). Private pharmacies could be able to deliver HIV self-testing kits giving the advantage of confidentiality, anonymity, and time savings, in particular for those reluctant to visit CBOs. The recruitment of participants using a respondent-driven sampling method could provide the opportunity to reach MSM and TGW outside the network of CBOs.

Objective: This pilot study aims to evaluate the feasibility of free HIV self-testing delivery by a private pharmacy combined with a respondent-driven sampling method to improve HIV testing among MSM and TGW in Phnom Penh, Cambodia.

Methods: Both qualitative and quantitative approaches are used in this prospective feasibility study. The protocol was approved by the National Ethics Committee for Health Research in Cambodia (N0 351 NECHR). MSM and TGW aged more than 18 years old will be recruited via a respondent-driven sampling method with seeds recruited at hot spots and on social networks. The seeds will then distribute electronic and paper coupons to their networks physically and via social media, messaging, and calling applications. Each recruited peer will bring the coupon to receive direct and free access to one HIV self-testing kit at partner pharmacies as well as 10 additional coupons to recruit members of their networks. As for quantitative analysis, data from the study website will be imported, appended into a single matrix using Stata version 18SE (StataCorp), and analyzed using descriptive statistics, with a statistical significance level of .05. After 6 months, a qualitative assessment will be conducted among users, providers, and policymakers or key stakeholders to evaluate the acceptability and appropriateness of the strategy and to identify the barriers, facilitators, and recommendations. All transcripts will be analyzed according to the 6-phase reflexive thematic approach by Braun and Clarke. The results will be reported by participant-based and provider-based issues. QSR NVivo V.14 for Windows will be used to manage the data.

Results: The study was funded by Agence nationale de recherches sur le sida, les hépatites, et les maladies infectieuses émergentes (ANRS) in September 2023. Approval of the study protocol was successfully obtained from the NECHR in Cambodia and the Commission Nationale de l'Informatique et des Libertés (CNIL) in France (Autorisation Tacite) in February 2025. Data collection will be conducted between September 2024 and December 2025. The initial results are expected to be published in February 2026.

Conclusions: This public-private partnership intervention could allow the hidden population of MSM and TGW in Phnom Penh to be reached and tested.

Trial Registration: ClinicalTrials.gov NCT05745168; https://clinicaltrials.gov/study/NCT05745168

Réfléchir sur les cancers du sein en pluridisciplinarité et à la lumière des rapports sociaux de genre : retour réflexif sur le projet SENOVIE

Joseph LARMARANGE — 2024-07-09T09:56:45Z

Réfléchir sur les cancers du sein en interdisciplinarité et à la lumière des rapports sociaux de genre : retour réflexif sur le projet SENOVIE

Clémence Schantz , Sarah Boisson , Joseph Larmarange , Luis Teixeira

XXIIe Congrès International des Sociologues de Langue Française, AISLF, Jul 2024, Ottawa, Canada

Communication dans un congrès

hal-04639785

Auteures

Clémence Schantz, avec Sarah Boisson, Joseph Larmarange et Luis Teixeira

Résumé

Le projet SENOVIE documente les vécus de femmes atteintes d'un cancer du sein dans plusieurs pays, s'inscrivant dans une vision globale des circulations des femmes et des ressources thérapeutiques. La particularité de ce projet est sa dimension internationale, avec des terrains au Bénin, France, Mali, Cambodge, et sa démarche intersectorielle avec des chercheur‧es universitaires venant de différentes disciplines (médecine, géographie, démographie, sociologie, anthropologie, santé publique), mais aussi des professionnel‧les de santé, et des associations de patientes. Nous proposons dans cette communication de présenter les enjeux d'une telle articulation disciplinaire sur un sujet au coeur de rapports de pouvoir liés au genre et adoptant une posture féministe. Sur quelles bases communes peuvent s'entendre et se rendre complémentaires ces différentes disciplines ? Quelles tensions et enjeux épistémologiques émergent de cette pluridisciplinarité ? Quelle compréhension des enjeux liés au genre par les différents acteurs et actrices ? La communication présentera un retour réflexif des membres de l'équipe sur des données et travaux du projet SENOVIE et leur analyse sous un prisme interdisciplinaire. Elle présentera les questionnements et défis que cette approche soulève.

Communication présentée au XXII^e Congrès International des Sociologues de Langue Française à Ottawa le 9 juillet 2024.

SENOVIE

Joseph LARMARANGE — 2024-07-02T17:15:15Z

Responsable scientifique

Clémence Schantz

Partenaires

Liste complète sur https://www.ceped.org/senovie

France

IRD
Ined
CHU Saint-Louis (Senopôle), Paris
Hôpital Delafontaine, Saint-Denis
Inserm
UPEC
Université Paris Nanterre

Mali

Faculté de Médecine et d'Odontostomatologie de Bamako
Association « Les Combattantes du Cancer », Bamako
INSP, Bamako
Centre de Santé de Référence de la Commune 2, Bamako
Hôpital du Mali, Bamako

Bénin

CNHU, Cotonou
Ministère de la santé, Cotonou
CHU-MEL, Cotonou

Cambodge

Hôpital Calmette, Phnom Penh
Douleurs sans frontière
Université des Beaux-Arts

Financements

Résumé

Le cancer du sein est le cancer le plus fréquent au monde. Dans de nombreux pays des Suds, les ressources thérapeutiques sont faibles, ce qui amène certaines femmes en quête de soins à quitter leur pays. Avec une approche biographique mixte (à la fois qualitative et quantitative), nous retraçons les parcours de vie de ces femmes et cherchons à préciser ce qu'impliquent ces mobilités thérapeutiques en termes de vécus et de ruptures biographiques. Afin d'avoir une vision globale de ces circulations, et afin de saisir les raisons qui amènent certaines femmes à partir, nous menons cette recherche en France (région Ile de France) mais aussi en Afrique de l'Ouest (Mali, Bénin) et Asie du Sud-Est (Cambodge). Avec le souci constant de co-contruire nos connaissances, et en impliquant des chercheures, des soignantes et des associations de femmes, cette recherche souhaite contribuer à la lutte contre les inégalités sociales de santé et à la mise en lumière de ces cancers en Afrique de l'Ouest et en Asie du Sud-Est.

Mots-Clés

Migrations, Cancers, Genre, Afrique, Asie

Zones géographiques (terrains de recherche)

France, Mali, Bénin, Cambodge

Calendrier

2021-2026

Dernières publications

How a quantitative biographical approach can help in understanding the complex intersections of breast cancer, migration and gender ? The case of the SENOVIE France study

Karna Coulibaly , Clémence Schantz , Luis Teixeira , Gaetan Des Guetz , Laurent Zelek , Joseph Larmarange , Anne Gosselin

SLLS Annual Conference 2025, Society for Longitudinal and Lifecourse Studies, Sep 2025, Fribourg (Suisse), Switzerland

Communication dans un congrès

hal-05332921

The contribution of a quantitative biographical approach in studying the social and health trajectories of immigrant and French-born women receiving breast cancer care in the greater Paris area

Karna Coulibaly , Clémence Schantz , Annabel Desgrées du Loû , Anne Gosselin

22nd IMISCOE Annual Conference, IMISCOE, Jul 2025, Auberviliers, Campus Condorcet, France

Communication dans un congrès

hal-05332880

Global therapeutic mobilities and cancer: a scoping review

Clémence Schantz , Sarah Boisson , Léa Prost-Lançon , Emmanuel Bonnet , Aurélien Dancoisne , Myriam Baron , Audrey Bochaton

BMJ Open, 2025, 15 (6), pp.e089780. ⟨10.1136/bmjopen-2024-089780⟩

Article dans une revue

hal-05124533

Knowledge transfer interventions on cancer in Africa and Asia: a scoping review

Julie Robin , Clémence Schantz , Madani Ly , Bakary Abou Traore , Kadiatou Faye , Aurélien Dancoisne , Valéry Ridde

BMC Cancer, 2025, 25 (1), pp.704. ⟨10.1186/s12885-025-14061-8⟩

Article dans une revue

hal-05111610

A Life course approach to investigate breast cancer and migration in the greater Paris area: the SENOVIE study protocol

Karna Coulibaly , Clémence Schantz , Luis Teixeira , Annabel Desgrées du Loû , Gaëtan Des Guetz , Hamid Hocini , Laurent Zelek , Joseph Larmarange , Anne Gosselin

BMJ Open, 2025, 15 (4), pp.e095759. ⟨10.1136/bmjopen-2024-095759⟩

Article dans une revue

hal-05019538

Réfléchir sur les cancers du sein en interdisciplinarité et à la lumière des rapports sociaux de genre : retour réflexif sur le projet SENOVIE

Clémence Schantz , Sarah Boisson , Joseph Larmarange , Luis Teixeira

XXIIe Congrès International des Sociologues de Langue Française, AISLF, Jul 2024, Ottawa, Canada

Communication dans un congrès

hal-04639785

Associations de lutte contre les cancers du sein en Île-de-France : quelles implications auprès des femmes immigrées d'Afrique subsaharienne ?

Clémence Schantz , Marie Bottin , Léa Prost , Louise Ludet , Gaëtan Des Guetz , Luis Teixeira , Myriam Baron , Groupe Senovie

Santé Publique, 2024, 36 (4), pp.47-59. ⟨10.3917/spub.244.0047⟩

Article dans une revue

hal-04730706

The challenge of radiotherapy in the fight against cancer in French-speaking West Africa

Clémence Schantz

The social and political lives of new cancer technologies in the global South, Fondation Brocher, Jun 2024, Geneva, Switzerland

Communication dans un congrès

hal-04612608

Amazons in Mali? Women's experiences of breast cancer and gender (re)negotiation

Clémence Schantz , Abdourahmane Coulibaly , Kadiatou Faye , Drissa Traoré

Social Science & Medicine, 2024, 348, pp.116874. ⟨10.1016/j.socscimed.2024.116874⟩

Article dans une revue

hal-04593224

Plan de gestion des données du projet SENOVIE France

Anne Gosselin , Karna Coulibaly , Joseph Larmarange , Clémence Schantz

Institut de Recherche pour le Développement (IRD). 2024

Rapport

hal-04563793

Voir la liste complète des publications

Pilot implementation of HIV self-testing delivery in private pharmacies combined to a Respondent Driven Sampling method to improve HIV testing for MSM and TGW in Phnom Penh

Joseph LARMARANGE — 2022-04-28T16:15:56Z

Pilot implementation of HIV self-testing delivery in private pharmacies combined to a Respondent Driven Sampling method to improve HIV testing for MSM and TGW in Phnom Penh – ANRS 0100s: a prospective feasibility study (Preprint)

Chhavarath Dary , Olivier Ségéral , Joseph Larmarange , Emilie Mosnier , Mohamed Ben Mechlia , Vichea Ouk , Bruno Spire , Vonthanak Saphonn

2024

Pré-publication, Document de travail

hal-04678769

Responsables scientifiques

SAPHONN Vonthanak (University of Health Sciences of Phnom Penh)
SPIRE Bruno (SESSTIM)

Partenariat

Financement

ANRS

Abstract

Primary objective

Evaluate the feasibility of HIV self-testing (HIVST) delivery by a private pharmacy network among men who have sex with men (MSM) and transgender women (TGW) recruited through a classic and digital Respondent Driven Sampling method to improve HIV testing in Phnom Penh, Cambodia

Secondary objectives

Evaluate the acceptability and appropriateness of the strategy
Identify barriers and facilitators
Estimate the linkage to confirmatory testing for those with a reactive test and linkage to HIV care and ART for those with a positive confirmatory HIV test
Estimate linkage to pre-exposure prophylaxis (PrEP) services for negative participants
Estimate the characteristics of participants and compare to those reported in Integrated Biological and Behavioral Survey (IBBS 2019) for MSM and TGW in Cambodia
Evaluate the adherence of participants to a 6-monthly repeated HIV testing

Methodology

An interventional pilot study using a mixed qualitative and quantitative approach will be carried out in order to evaluate the feasibility, acceptability and appropriateness of the strategy and to identify barriers and facilitators.

The participant recruitment method will be designed as a Respondent Driven Sampling (RDS) by recruiting initial seeds both at hotspots and on social networks. Prior to seed recruitment, a consultative meeting will be conducted in order to optimise the selection criteria of the seeds. The seeds will then distribute electronic and paper coupons to their networks physically and via social media, messaging and calling applications such as Twitter, Whatapp and Telegram (e-coupons). Each recruited participant will bring the coupon to be scanned at partner pharmacies to receive direct and free access to one HIVST kit. Partner pharmacies with a proper dedicated room/space securing privacy and secrecy in Phnom Penh are the study sites. There, trained community workers who get notified by partner at each visit of participant will do the study visit including information/consent, e-CRF filling and give a link of an external website to send the HIV test results and receive information or advices. These recruited individuals will be considered as wave 1 of recruitment and will each receive 10 additional coupons to recruit the members of their networks. The next round of individuals recruited and enrolled will be considered as wave 2, and so on.

After 6 months, a qualitative assessment via focus groups will be conducted among MSM, TGW and pharmacists to evaluate feasibility, acceptability and appropriateness of the intervention and to identify barriers and facilitators.

Several ART sites/HIV clinics particularly in charge of key populations will be specifically selected as participating centers in order to collect information on linkage to care or prevention services for positive and negative participants, respectively.

Each participant will be followed during 18 months and encouraged to perform a 6-monthly HIV testing during this period.

Expected enrolment

A pragmatic approach is carried out in which the enrolment will be stopped at the end of the inclusion period or if the number of participants reaches a maximum of 1500.

Zone géographique

Phnom Penh, Cambodge

Calendrier

2022-2024

Joseph Larmarange

Pilot Implementation of HIV Self-Testing Delivery in Private Pharmacies Combined With a Respondent-Driven Sampling Method to Improve HIV Testing for Men Who Have Sex With Men and Transgender Women in Phnom Penh (ANRS 0100s): Protocol for a Prospective Mixed Method Feasibility Study

Pilot Implementation of HIV Self-Testing Delivery in Private Pharmacies Combined With a Respondent-Driven Sampling Method to Improve HIV Testing for Men Who Have Sex With Men and Transgender Women in Phnom Penh (ANRS 0100s): Protocol for a Prospective Mixed Method Feasibility Study

Authors

Abstract

Réfléchir sur les cancers du sein en pluridisciplinarité et à la lumière des rapports sociaux de genre : retour réflexif sur le projet SENOVIE

Réfléchir sur les cancers du sein en interdisciplinarité et à la lumière des rapports sociaux de genre : retour réflexif sur le projet SENOVIE

Auteur·es

Résumé

SENOVIE

Responsable scientifique

Partenaires

Financements

Résumé

Mots-Clés

Zones géographiques (terrains de recherche)

Calendrier

Dernières publications

How a quantitative biographical approach can help in understanding the complex intersections of breast cancer, migration and gender ? The case of the SENOVIE France study

The contribution of a quantitative biographical approach in studying the social and health trajectories of immigrant and French-born women receiving breast cancer care in the greater Paris area

Global therapeutic mobilities and cancer: a scoping review

Knowledge transfer interventions on cancer in Africa and Asia: a scoping review

A Life course approach to investigate breast cancer and migration in the greater Paris area: the SENOVIE study protocol

Réfléchir sur les cancers du sein en interdisciplinarité et à la lumière des rapports sociaux de genre : retour réflexif sur le projet SENOVIE

Associations de lutte contre les cancers du sein en Île-de-France : quelles implications auprès des femmes immigrées d'Afrique subsaharienne ?

The challenge of radiotherapy in the fight against cancer in French-speaking West Africa

Amazons in Mali? Women's experiences of breast cancer and gender (re)negotiation

Plan de gestion des données du projet SENOVIE France

Pilot implementation of HIV self-testing delivery in private pharmacies combined to a Respondent Driven Sampling method to improve HIV testing for MSM and TGW in Phnom Penh

Pilot implementation of HIV self-testing delivery in private pharmacies combined to a Respondent Driven Sampling method to improve HIV testing for MSM and TGW in Phnom Penh – ANRS 0100s: a prospective feasibility study (Preprint)

Responsables scientifiques

Partenariat

Financement

Abstract

Zone géographique

Calendrier

Auteures